3. Systemic Sclerosis and Mixed Connective Tissue Disease.
نویسندگان
چکیده
منابع مشابه
[Mixed connective tissue disease].
Mixed connective tissue disease deserves to be a distinct disease entity due to the persistent citation of this disease in the literature since the original description by Sharp in 1972, in spite of the presence of several criticisms against the independency of this disease. The characteristic features of mixed connective tissue disease are: 1) the presence of anti-U1snRNP antibody with high ti...
متن کاملLong term follow-up of children with juvenile systemic sclerosis, mixed connective tissue disease and pulmonary disease
Results Six (5 female, 1 male) children with J-SSc or J-MCTD were studied. The age at the disease onset ranged from 2–13 yrs. The follow-up duration was 6–18 yrs (mean 10 yrs). Four children had J-SSc and two had J-MCTD. Three children developed interstitial lung involvement proven by HRCT or chest x-ray. Pulmonary arterial hypertension (PAH) occurred in three children, two with J-SSc and one w...
متن کاملMixed connective tissue disorder and Castleman's disease.
We present a 16-year-old girl who presented with polyarthritis in association with Raynaud's phenomenon, malar rash, oral ulcers, photosensitivity and alopecia of 6 months duration. On evaluation, it emerged that she had a mixed connective tissue disorder with a mesangio-proliferative glomerulonephritis. Her Chest radiograph revealed a well defined left mid and lower zone opacity with evidence ...
متن کاملSystemic sclerosis and related connective tissue diseases: present and future
In April 2006, 30 international experts gathered in Athens, Greece, to discuss systemic sclerosis (SSc) and related connective tissue diseases (CTDs). SSc is a clinically heterogeneous and complex disease that is characterized by vascular dysfunction, vascular and extravascular fibrosis, and characteristic immune derangements, and for which few treatment options are available. The aims of the C...
متن کاملAssociations between circulating endostatin levels and vascular organ damage in systemic sclerosis and mixed connective tissue disease: an observational study
INTRODUCTION Systemic sclerosis (SSc) and mixed connective tissue disease (MCTD) are chronic immune-mediated disorders complicated by vascular organ damage. The aim of this study was to examine the serum levels of the markers of neoangiogenesis: endostatin and vascular endothelial growth factor (VEGF), in our unselected cohorts of SSc and MCTD. METHODS Sera of SSc patients (N = 298) and MCTD ...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2010
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.99.2407